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Matt and Kevin discuss a new paper about the “subfornical organ” which (once again) undermines the idea of immune privilege, and also points to an interesting evolutionary question: why would T-cells migrating from fat to the brain affect hunger response?
Also, Matt tries to speak through virus-mediated destruction of his trachea, and Kevin keeps trying to make Buddhist immunology a thing.
Links
The paper: The subfornical organ is a nucleus for gut-derived T-cells that regulate behavior
Audiommunity episode 17 about the then-surprising notion of lymphatics in the brain
Audiommunity episode 19 about helminths and brain autoimmunity
